2,2-Difluoroethanol
Difluoroethanol (DFE), 2,2-Difluoroethyl alcohol, β,β-Difluoroethyl alcohol, 2,2-Difluoro-ethanol, 2,2-difluoroethan-1-ol, 'Ethanol, 2,2-difluoro-', is the organic compound with the formula CHF2CH2OH. This colourless, water-miscible liquid has a smell reminiscent of ethanol. Due to the electronegativity of the difluoromethyl group, this alcohol exhibits a stronger acidic character compared to ethanol. Thus, DFE forms stable complexes also with heterocycles (e.g. THF or pyridine) through hydrogen bonding.
Uses
2,2-Difluoroethanol is an important intermediate in the synthesis of active agrochemical and pharmaceutical ingredients.
Package & Transport
Package Size: 250kg/drum
UN Number: 1987
Transport/Additional information:
ADR Excepted quantities (EQ): E2
Limited quantities (LQ) 1L
Transport category 2
Tunnel restriction code D/E
UN "Model Regulation": UN1987, ALCOHOLS, N.O.S., special provision 640D (2,2-Difluoroethanol), 3, II
Notice
1. Keep away from heat, sparks, and flame. Flammables-area.
2. Keep container closed when not in use. Corrosives area.
3. Keep containers tightly closed.
2,2,2-Trifluoroethanol
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| Molecular formula | C2H4F2O (CHF2CH2OH) |
| Molar mass | 82.05 g/mol |
IUPAC Name
Identifiers
| CAS number | 359-13-7 |
| EC number | - |
| ChemSpider | 119963 |
| BRN number | 1731617 |
| PubChem | 136187 |
| Jmol-3D images | Image |
SMILES[show]
InChI[show]
Properties
| Appearance | Colorless liquid |
| Density | 1.29 g/cm3 |
| Melting point | -28℃ (261.15 K) |
| Boiling point | 96℃ (369.15 K) |
| Refractive index | 1.338 |
| Solubility in water | miscible |
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